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Question

Posted on: August 23 2016

We need to make cimetidine syrup 50 mg/ml for a child of 5 years.

We wondered why HCl 1 N 16 ml should be added to the preparation?

Answer

  This product is soluble in water (50 mg/ml), with heat   as needed, are a clear, colorless to faint yellow   solution. The addition of dilute HCl has been reported to enhance the solubility of this product.   I suspect that for the concentration, you should prepare 16 ml HCl 1 M will not be necessary; maybe a few drops