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Question

Posted on: March 6 2013

Is there a way to eliminate the bitterness of pseudoephedrine syrup for children?

  • case: Girl of 7 years with unstable bladder
  • treatment:
    1/2 comp Driptane
    1 teaspoon pseudoephedrine syrup 120mg/5ml
  • problem: Preparation of syrup: PS. Ephedrine dissolved in water further Complement with raspberries syrup (also tried with orange blossom syrup). The solution remains seemingly unsteady: the taste varies from unpleasant to very pronounced (not absorbed) bitter.
  • question: statement? Change in efficacy? toxicity?

Answer

There are only two liquid forms known from pseudoephedrine: Actifed syrup and pseudoephedrine syrup for children NF 6 but at a much lower dosage, respectively 30 mg and 15 mg per coffee spoon. Therefore, it is not ruled out that a dosage of 120 mg/5 ml indicates the problems mentioned. Considering most medicines, which contain pseudoephedrine under Solid form, it is advisable to also prepare capsules here with 120 mg per capsule. As a diluent, best mannitol or sorbitol can be used. For administration, the capsule can be opened and the contents mixed with jelly or yoghourt.