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Question

Posted on: October 7 2019

Saponinie Coaltar Dilute with water to prepare a lotion for the scalp

Composition: Saponinecoaltar 3 G, prednisolone 0.5 g, aqua AD 100 g Prednisolone is not soluble in water. Saponin Coaltar is alcohol-based. But 3 G is probably insufficient to keep prednisolone in solution when diluting with water? And what with Saponin Coaltar when diluting with water???

Answer

I suggest to try the following

Tarreer Beaker and stirring rod   (T g)  

Weigh   20   g   propylene glycol and dissolve the prednisolone   in it  . Add the Saponin Coaltar and 15 g Tween 80. Mix with the rudder rod until homogeneous. Place beaker with stirrer on balance and gradually add stirring water to T + 100