Question
Posted on: November 13 2017Riluzole 5mg/mL suspension
Answer
Following formula was recovered for a 0.5% suspension:
Riluzole 500 mg; sorbitol 40 g; Veegum 1 G; Xanthan gum 100 mg; Tween 80 150 mg; After saccharinate 100 mg; Mint water based on Aqua Conservans up to 100 ml
You obviously have to deal with the composition of the tablet. The active substance in this medicine is riluzole. -The other ingredients are:
core: anhydrous calcium hydrogen phosphate, microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, croscarmellosenatrium. Coating: Hypromellose, Macrogol 6000, titanium dioxide (E171).
Given the presence of some excipients, which can give a certain viscosity, the addition of Veegum and xanthan gum may be superfluous. Practice will have to show this out. If you have insufficient viscosity, the thickening agent can still be added at the end.