Preparation of AMPHOTERICINE B (Fungi Zone) 0.1% eye drops.

I suppose you will leave from Fungi zone. After dissolving the powder with the solvent you get 10ml solution 5mg/ml. This means that you need 2 ml for a collyre of 10ml 0.1%. This solution allows you to create 5 eye droplets. But there is a problem of preservation.

after transferring 2ml of Fungi zone solution into a sterile eye dropper vial is further diluted with 8 ml sterile water for injections. After all, the solution Fungi zone contains the required humidifier and buffer for the stability of the colloid solution. This is incompatible with electrolites (no physiological serum) and of course also with some medicines. Both the Fungi zone solution and the added water are sterile and therefore membrane filtration is not necessary. In addition, it is not applicable to a colloid solution.

the eyedropper solution is stable for 7 days when stored in the refrigerator. If discoloration or cloudy, the solution should no longer be used. It is not ruled out that any pain is encountered when administered.