Question
Posted on: March 6 2013Please advice related to the preparation of next eye ointment: NaCl 0.5% Indometacine 0.5% Yellow Vaseline 8g Liquid paraffins 1g wool fat 1g
Answer
to avoid scratches, NaCl is dissolved in 1 ml of sterile water; This amount is deducted from the 8g Yellow petroleum jelly.
the fats can be sterilized without problem at 150 ° C in a warm air furnace as also 50 mg NaCl weighed on a clean watch glass and covered with aluminum foil. About sterilization at 150 ° C of indomethacin I cannot find any data. I suspect it can. Check if the product discolours! The material and the ointment tube (without cap!) can, after packing, be sterilized in an autoclave. After sterilization, cooling and possibly drying of constituents and material, a sterilized mortar 50mg NaCl is dissolved in 1ml of sterile water and this solution is used to rubbed the sterilized indomethacin. After that, the sterilized Excipi &etuml; NS is gradually being assisted. The ointment is aseptically packaged in a sterilized and dried tube. The inside of the tube is washed with antiseptic solution.