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Question

Posted on: September 7 2015

Phenylmercuriborate solution is not available. Can this be replaced in the preparation of next eye drops?

R/Nafluorescein and Oxybuprocanehcl

Answer

As a preservative comes with what is currently still available only Nipagine-Nipasol are eligible.  

According to the common theory, an incompatibility between fluorescein and oxybuprocaineH + could occur. I underline "can".  

For the isotonic I would use glucose here that is non-ionogen.