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Question

Posted on: March 6 2013

Our opthalmologists ask glycerol/water 50% eye drops for deswelling of the eye prior to surgery.

Which sterilization method do we best apply? Sterile filtration seems to us difficult owv viscosity, autoclaving: Stability at higher T? (Merck and Martindale mention nothing)

Answer

A clear hyperosmotic solution with low water actvity. So a bad breeding ground for germs. Therefore, I would propose to sterilize with the method of Deussen. However, the collyrevials are sterilized in advance at 121 ° C.