I have a prescription for sulffadiazine suspension 100ml sulfadiazine 100mg/ml for a 2 month baby.

First possibility

Sulfadiazine 10g Excipiens xanthan gum 30g Citric acid 650mg Sodium citrate 4.750 g Sugar syrup 30g AQUA CONSERVANS AD 100ml In a mortar sulfadiazine rub with sugar syrup to add a homogeneous paste and then excipient xanthan gum under Stirring Dissolve citric acid and nacitate in 25ml water The aqueous solution add to the contents of the mortar together with 0.5 g of the Contrac. Hydroxybenzoate Solution FN VI and mix. Take a bottle and fill them with 100ml of water; Tick a mark at the level of the water surface. Pour the contents of the mortar into the bottle and rinse with water until the volume reaches 100ml.

Second possibility

The intent of Method 2 is to make very fine sulfa particles by precipitating in situ.

Sulfadiazine 10g Excipiens xanthan gum 30g Citric acid monohydrate 4.0 g Sodium hydroxide 2.0 G Sugar syrup 30g AQUA CONSERVANS AD 100ml Method

Loose in Beaker I 4g citric acid 1aq on in 10ml water Dissolve in second Beaker II 2g NaOH in 20ml water and cool off; Add to this solution stirring the sulfa well. Mix until fully resolved Take a perfect big mortar with accompanying Stamper In this mortar, apply 30g of excipient xanthi and 30g syrup; Mix and add under stirring contents of Beaker II Pour into the same mortar the contents of Beaker I under quick stirring; Take a suitable bottle and pour 100ml of water into the bottle; Draw a gauge at the level of the liquid surface Pour the contents of the mortar into the bottle and add 0.5 g of Contrac Hythe Benzoate solution FN VI and Mix Apply to volume with water, which is used to rinse the mortar before adding to the bottle. Comments

Sugar syrup can be replaced by sorbitol 70% Apparently NaOH is difficult to sell within the normal pharmaceutical circuit. Ammonia is available as 10% or 25% solution according to the Eur. Pharm. Two ounces of NaOH corresponds to 8.5 g or 3.4 g 10% or 25% solution respectively. You do not need to use excipient Xanthan if your stock is up; This can be replaced without problem. But it's easy. If the viscosity is still to be reduced, it can also be worked with water sweetened with an artificial sweetener, provided that the amount of parabens is adjusted.