Question
Posted on: March 6 2013I had a question about following preparation: Hydrocortisone acetate 1g prednisolone 0.3 g liquor Carbonis detergent 9g urea 3g lipophilic cream TMF AD 100g
Answer
rub in a tarred metal or porcelain dish, the prednisolone and the hydrocortisone acetate with the LCD and then evaporate on a lightly heated plate the alcohol of the LCD. The weight difference is replaced by starch, which is mixed under the contents of the scale. Note the total weight mixture (eg = X) in the scale and calculate the amount of various constituents needed for the preparation of a total of 97-X g lipophilic cr è me. Prepare this amount of CR è me and dissolve the 3 G urea in the water phase. Let this cr è me completely cool and rub the powder mass in the bowl with this urea-containing lipophilic cr è me.
an alternative method would exist to replace the weight difference obtained after evaporating the alcohol by Arlacel C. Roughly along the lines of what you already did.