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Question

Posted on: May 10 2013

I am looking for a product that has similar effect to CREMOPHOR EL

Cremophor EL is quite costly and usually has a short expiration date. (75 euro for 250 ml). I use this product for the preparation of Minoxidil 5% lotion.

Answer

I can make you a proposal without guarantees because I should test it out.  
 
try to replace Crempophor EL with either Tween 80 or Cetomacrogol 1000. Personally, I would prefer Tween, which I would add at least 5 G. Make the preparation grosso modo but keep the water behind. If the quantities are expressed in grams, then it is easy to work; However, it is ad 100 ml then it is slightly harder. Add water to the end, observe the formation of a cloudy; If yes add additional 2.5 G Tween 80.