Question
Posted on: June 14 2017How can you process L-arginine in a syrup?
Answer
Give a statement to the discoloration with grenadine is very difficult because we usually have to do with a very complex system of all sorts of chemical compounds.
At a German university, a thesis was made on the administration of arginine. It is clear that preference is given to solid forms like e.g. granules, pellets...
Granulate Preparation in the pharmacy is a not impossible operation but requires a bit of experience and certain equipment. Not so sophisticated (a not too fine sieve) but usually not present in the pharmacy. In the kitchen?
There is also the possibility to prepare a solution. In the thesis is opted for a 10% arginine HCl solution. Various compositions were tested. The next was finally pushed forward; Arginine HCl 10%, Na2EDTA 0.1%, sucralose 0.05%, cherry syrup 10% , honey 5%, banana aroma 0.02% and water up to 100 ml.
The pH of the solution is set to 6.5.
Other excipients, which could still qualify, are: Appelsien aroma (maybe Orange blossom?; can also be orange peel if the solution tastes bitter)
Can sucralose (200 à 300 x sugar) be replaced by another sweetener if after saccharin or aspartame?? We need to avoid incompatibilities + against-and consequently we prefer aspartame (150 X sugar)
Sucralose has the big advantage of not being ionogen. But maybe also just sugar syrup or sorbitol 70% non-crystallizable e.g. for 50% usable ?
Store in the refrigerator