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Question

Posted on: March 6 2013

Ephedrine sulfate is no longer available. Which is the solution for these nasal drops? Argyrol 100mg Ephedrine sulfate 100mg physiological serum 30ml

Answer

My suggestion is to use ephedrine base, which we neutralize with acetic acid. This will require a small calculation. It is better and safer to neutralize with diluted acetic acid!
We depart from glacial acetic acid containing 100% M/M vinegar and I suspect this is best diluted to 1% M/M. We make isotonic with after acetate so that we ë run a buffer system. After all, physiologically serum is not usable.