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Question

Posted on: March 6 2013

A doctor prescribes the following ear drops, which appear rather a cream.

Prednisolone 100mg
Chlorhex. Digl. opl. 20% 50mg
Glycerin 4g
cetyl alcohol 2g
natriumlaurylsulfaat100mg
aq cons ad 20ml < br/> There is still a second problem: an interaction between the Chlorhex. OPL and After-lauryl sulfate, so that the emulsion stability is not retained.

Answer

As far as the first point is concerned, you are right. What I do wonder about is the use of an O/W emulsion cream where water-free preparations are often inserted into the ear, especially for the treatment of the outer ear. If the preparation is too viscous, you can reduce the cetyl alcohol. To circumvent the specified incompatibility, replace nalauryl sulfate with Cetomacrogol.