To recipes helpdesk

Question

Posted on: March 6 2013

Do you have a suitable ovule base and possibly preparation method for Neomycin 35 mg Nystatin 100 000 IU polymyxin B sulfate 35 000 IU FAC ovule

Answer

Given the stability I would prefer a fat base such as Witepsol 45 or H 15 (H 15 maybe preferable). The preparation cannot make any major problems; Only the mixture of medicinal products should be mixed with lactose up to 1 g per ovule of 4 G to ensure homogeneity. Best to store the Ovulen in the refrigerator.