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Question

Posted on: March 6 2013

Do you have data on the magistal preparation of phenytoin-Suppos?

Which suppobasis is best used for this and do you have data around serum concentrations of phenyto ï ne after rectal administration?

Answer

The only thing I can find in the literature is to use it to advise against a PEG base. So I would use the universal Witepsol base. Remains about the question: "Do we use Difanto ï ne or his sodium salt?" I would start with the sour form and ask the Doctor and the Pati ë NT if there is a good response. If not, then it may be considered switching to Nadifanto ï NE.