Question
Posted on: October 28 2015Can a stock solution be prepared with Urfamycine?
Answer
store at room temperature (15-25 °C). The prepared solution is usable for several hours at room temperature.
There is such a thing as the Q10 rule, which says that the stability of a product doubles for every ten degrees we reduce the temperature. The reverse works of course as well.
So suppose at room temperature (20 °C) 2 hours stable; at 10 degrees 4 hours and at-5 ° C +/- 10 hours.
Pulmicort is a suspension and for this product is clearly indicated do not freeze. After all, a lowering of the temperature can make changes to the particle size by lowering the dissolved fraction. Little is completely insoluble!!
I fear that the client will have to compose his solution for inhalation itself, taking into account the quantities and proportions prescribed by the physician.