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Question

Posted on: March 25 2018

Budenoside 1mg/10ml in xanthan gum

Prescription for oral suspension with Budenoside 1mg/10ml in xanthan gum for esophageal inflammation. Patient takes 2 X 10 ml per day. What about shelf life? Stability? Add additional excipients?

Answer

You can prepare: Budenoside 60 mg; xanthan gum 6   g; After saccharinate 450 mg  ; Glycerin 30 ml  ; Na2EDTA 300 mg; Flavor (banana?) QS; Aqua Conservans AD 300 ml  

This is a quantity for 15 days. You can double that; Then the customer has for 1 month.   The problem of microbiological stability is allight greater than of the chemical there budenoside is water insoluble. But prepared in hygienic conditions with freshly cooked water  ! I hope that the suspension remains shakable.