How do I use Liquifine® ?

Liquifine® makes it possible to produce high quality pharmaceutical suspensions in an easy manner.

Therefore, you first have to check the compatibility of your active ingredient with Liquifine®. The table below can help you with this decision. For all the components in this table, there are also detailed production protocols available on the 'Recipe Helpdesk'.

Preparation instructions:

Liquifine® pH4 Liquid 500 ml

Weigh the required quantity of active substance and reduce the particles to a fine powder by the use of a mortar and vessel, if necessary.

Humidify the powder with a limited quantity of Liquifine® and homogenize.

Add Liquifine®, following the geometric dilution method, to the desired volume.

Label the recipient with 'Shake before use'.

Liquifine® pH4 Liquid 500 ml + NaHCO3

Weigh the required quantity of active substance, as wel as 4.04 g sodium hydrogencarbonate (per 100 mL suspension), and homogenize. 

Humidify the powder with a limited quantity of Liquifine® and homogenize.

Add Liquifine®, following the geometric dilution method, to the desired volume.

Label the recipient with 'Shake before use'.

Liquifine® Alkalic dry

Weigh the required quantity of Liquifine® Alkalic dry (6.3 g per 100 mL suspension) and transfer it to the final recipient*.

Weigh the required quantity of active substance and transfer it also to the final recipient.

Shake firmly.

Add purified water to the desired volume and shake firmly until a homogeneous dispersion is obtained.

Label the recipient with 'Shake before use'.

* You can also use the pre-filled 100 mL bottles with mark line, which contain already the required amount of Liquifine® Alkalic dry.
 

As you can see, it is possible to use Liquifine® pH4 Liquid 500 mL + NaHCO3 as well as Liquifine Alkalic dry for the processing of acid sensitive components. The overview below can help you to make the right choice for your application.