Question
Posted on: March 6 2013Cool ointment with very high amount of salicylic acid and urea salicylic acid 30% urea 40% cold cream AD 100% dt 150g
Answer
I can assume that such amounts of salicylic acid and urea are not to be processed in cool ointment. With the amount of urea I can agree but 30% salicylic acid is huge. Too much according to me. The TMF gives a maximum concentration of 5%.
I suggest following CR% Egrave; Mebasis for:
Lanette N 24g Sorbic acid 150mg Cetiol V 16g Sorbitol 2.8 g Water up to 100g
In any case, prepare the cream first. Make the urea very fine and mix the fine powder with the cream. The urea must dissolve. Rub into a mortar salicylic acid with cetiol. And then gradually transfer the cream in parts to the salicylic acid. You will have to mix well because the cream is O/W and Cetiol is lipophilic. But I suspect that stirring well is to get the Cetiol + Salicylic acid under it.
Response (due to Apoth. Crynen) Beautiful cream with 40% urea, good to handle, nicely combable. We have added increasing amounts of salicylic acid after rubbing with Cetiol according to the proposed method. This gave a very nice result. Increase to 10% seems to me also possible, but the original 30% previously not feasible. I suspect that there was indeed a zero too much written.