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Question

Posted on: April 4 2023

Prepare nitrofurantoin suspension with liquifin

Is it possible to prepare a nitrofurantoin suspension for pediatrics with the liquifine orange suspension medium?

Answer

I suspect so. One point bothers me a bit. This is that the suspending agent used in the TMF guarantees a thixotropic whole. Thixotropic suspension medium is ideal for the physical stability of the suspension. Liquifine is a thixotropic product with pseudo-plastic properties and is suitable for this purpose. Extensive stability studies are not yet available in this combination. However, there is little risk because Liquifine has a neutral and uncharged composition. Depending on the viscosity, additional water can be added. The viscosity depends on which type of nitrofurantoin is used.