Question
Posted on: March 6 2013Podofylline Resin: The use is not recommended for use in the first line. If you have a suitable formulation for the use of Podofyllineresin in the second line, and the correct use of the
Its? < br/> In the Folia Pharmacotherapeutica June 2001, Nr. 28 (6), 54, the use of Podophyllotoxin and Podophyllin is described in Condylomata acuminata: podofyllotoxin 0.5% solution or 0.15% cr è me. No authorized raw material is available today so it cannot be prepared in practice.
Answer
There are a number of possibilities
- a simple solution of 25% Podophyllin resin in flaunable paraffin
- a tincture of 3.65% Podophyllin in alcohol 90 °
- a coll odium 5, 20, 25%
for the 5% is 24g antiseptic solution (AO) Added and 71g collodion elasticum PB V; For the 20% 20g AO and 60g collodion elasticum but apparently without castor oil (why?); For the 25% 19g AO and 56g collodion elasticum but apparently without castor oil.
I do not guarantee that the Podophyllin resin dissolves in 1.2 and 3 completely! - A 20% ointment in petroleum jelly
I have to end up with following recommendations in the preparation: wear gloves and glasses; avoid dust formation and clean the workshop with soap and water! After all, podophyllin can cause severe irritation by inhalation and contact with eyes and skin.