Question
Posted on: April 22 2018How can I dissolve ketoconazole in a clear shampoo.
Answer
After Laurylether-2 sulfate 40 g; Lauramide Acid (cocamide) diethanolamide 0.1 to 1%; NaCl 25% solution 4 ml; Citric acid 20% aqueous solution 0.5 ml; All 200 mg; Ketoconazole 2 G; Propylene glycol 5 ml, water purified QS 100 ml
Place in a beaker the Na laurylethersulfate and mix with any added perfume; measure 55 ml of water and pour into a beaker and add citric acid; Thicken the mixture with all NaCl
If the viscosity is too low, apply them with Cocamide DEA (Comperlan KD) to a maximum of 1%: Add slowly under stir, allow a time before adding a next small amount
Mix in a mortar all and ketoconazole and rub with propylene glycol to form a homogeneous paste; dilute with a small amount of shampoo base
Completely transfer the contents of mortar to the shampoo base and mix to homogenous. Check the pH, which = 6 à 6.5; Adjust if necessary.
Pour the whole quantity quantitatively into a measuring cylinder, using a panlikker. Check how much water should be added to bring on 100 ml.
Use the missing water to rinse the mortar and beaker.