Question
Posted on: November 9 2016Is a conversion according to the molecular weight always necessary if the physician prescribes the base form, if the raw material is only available in the salt form?
Answer
DSE situation is ambiguous. For Hibidil solution is mentioned 50mg/100 ml solution. The solution contains 50 mg chlorhexidinedigluconate per 100 ml.
For Chlorhexidinedigluconate Cream 1% is indicated 10 mg chlorhexidinedigluconate per G and 5.3 g 20% chlorhexidinedigluconate solution is used for 100 g. The reason why more than 5 G is used is due to the fact that the concentration of the concentrated solution of chlorhexidinedigluconate = 20% g/V. The density of this solution is > 1
Hydralazine has as mol. Gew. = 160 and hydrochloride = 196 or 196/160 = 1.0888. If you do not change you will make 8% error. I assumed that the purity approximates 100%.
Mirror How the TMF is working for folic acid.